Sculptra, manufactured by Dermik Laboratories (part of Aventis) and through Sinclair-IS Pharma in the UK, is a unique dermal filler that contains a proprietary formula of poly-l-lactic acid. Launched in the UK in 2000, it is unique in the dermal filler industry as it stimulates the skin to thicken through collagen neo-synthesis. This helps the treated areas to improve in appearance through reduced depressions or folds and helps mask volume loss. In clinical tests, Sculptra is proven to last for up to 2 years, in some cases longer. Generally two to three sessions are required.